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Structure of 6388-47-2
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2-Amino-3-chlorobenzoic acid features a strategically positioned chloro group flanking a primary amine and carboxylic acid, enabling dual functionalization in synthetic routes. This electron-deficient aromatic scaffold integrates readily into pharmaceutical intermediates and bioactive molecule frameworks under standard conditions.
2-Amino-3-chlorobenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted quinoline and benzimidazole scaffolds via cyclization reactions. Its ortho-functionalized structure provides excellent regiocontrol in coupling processes, while the amino and carboxylic acid groups offer complementary handles for derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scale-up and integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: