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Structure of 639520-70-0
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tert-Butyl (4-bromophenyl)(methyl)carbamate features a brominated aromatic ring paired with a sterically hindered tert-butyl carbamate group, enabling stable protection of primary amines. The methyl substitution enhances electronic tuning, while the para-bromo handle facilitates downstream coupling reactions in medicinal chemistry and materials synthesis.
tert-Butyl (4-bromophenyl)(methyl)carbamate serves as a stable, bench-ready building block for the synthesis of biaryl and heterocyclic scaffolds. The bromo group enables palladium-catalyzed cross-coupling reactions such as Suzuki and Buchwald–Hartwig transformations, while the carbamate functionality provides orthogonal protection for nitrogen. Its methyl substitution enhances solubility and reduces aggregation during purification, facilitating efficient downstream functionalization in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: