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CS-W001157 4
Total: USD 88.00

3,5-Difluoro-2-hydroxybenzaldehyde

  • CAS No. 63954-77-8

  • Cat. No. CS-W017964
  • Molecule weight158.10
  • Purity≥97%
  • MDL No.MFCD04039224

*For research and further manufacturing use only, not for direct human use.

3,5-Difluoro-2-hydroxybenzaldehyde|CS-W017964

Structure of 63954-77-8

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General Information

  • CAS No. 63954-77-8
  • Cat. No. CS-W017964
  • Purity ≥97%
  • MDL No. MFCD04039224
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄F₂O₂
  • Molecular Weight 158.10
  • Synonym(s) 3,5-Difluorosalicylaldehyde, 2,4-Difluoro-6-formylphenol
  • SMILES OC1=C(C=O)C=C(F)C=C1F

Description

3,5-Difluoro-2-hydroxybenzaldehyde features a strategically positioned hydroxyl group flanked by two fluorine substituents, enhancing electron withdrawal and enabling unique reactivity in electrophilic substitution. This bench-stable aromatic aldehyde integrates readily into synthetic routes requiring polarized carbonyl functionality under mild conditions.

Synthesis

  • Route1
    • In-stock
      2,4-Difluorophenol|CS-W013441
      367-27-1
    • null|null
      76-05-1
    • ~71%
    • In-stock
      3,5-Difluoro-2-hydroxybenzaldehyde|CS-W017964
      63954-77-8

    References

    • Beliaev, Alexandre; Wahnon, Jorge; Russo, Domenico Organic Process Research and Development, 2012 , vol. 16, # 4 p. 704 - 709
  • Route2
    • In-stock
      2,4-Difluorophenol|CS-W013441
      367-27-1
    • null|null
      100-97-0
    • ~80%
    • In-stock
      3,5-Difluoro-2-hydroxybenzaldehyde|CS-W017964
      63954-77-8

    References

    • Weidner-Wells, Michele A.; Fraga-Spano, Stephanie A. Synthetic Communications, 1996 , vol. 26, # 14 p. 2775 - 2781

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.4829
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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