Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 64248-57-3
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
1,2-Difluoro-3-iodobenzene is a fluorinated aromatic building block featuring ortho-fluorine and meta-iodine substituents on a benzene ring. This configuration enables selective cross-coupling reactions under palladium catalysis, leveraging the iodine moiety as a reactive handle. The electron-withdrawing fluorine groups enhance stability and modulate reactivity, facilitating efficient functionalization in complex molecule synthesis.
1,2-Difluoro-3-iodobenzene serves as a versatile building block in cross-coupling chemistry, enabling the construction of fluorinated biaryls and heterocycles under palladium-catalyzed conditions. The ortho-fluoro substituents enhance regioselectivity in subsequent functionalizations, while the iodine moiety provides high reactivity in Suzuki, Stille, and Negishi couplings. Bench-stable and readily purified by column chromatography, it functions as a key intermediate in the synthesis of pharmaceutical scaffolds and agrochemicals requiring controlled fluorination patterns.
|
GHS Pictogram :
|
GHS No : GHS02,GHS08
|
|
Signal Word : Danger
|
UN#: 1993
|
|
Class : 3
|
Packing Group : Ⅲ
|
|
Hazard Statements : H225-H304
|
|
|
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P331-P370+P378-P405-P501
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: