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Structure of 2265-92-1
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1,4-Difluoro-2-iodobenzene features a strategically positioned iodine atom flanked by two fluorine substituents, enabling selective cross-coupling reactions. The electron-withdrawing fluorines enhance reactivity in palladium-catalyzed processes while maintaining stability under standard conditions. This aryl iodide serves as a key intermediate for constructing complex fluorinated scaffolds in medicinal chemistry and materials science.
1,4-Difluoro-2-iodobenzene serves as a versatile building block in cross-coupling chemistry, enabling the construction of biaryl scaffolds under palladium-catalyzed conditions. The ortho-iodo and para-difluoro substituents provide orthogonal reactivity for sequential functionalization, while the molecule exhibits excellent bench stability and compatibility with standard reaction protocols. Its defined substitution pattern facilitates predictable coupling outcomes, making it ideal for the synthesis of fluorinated aromatic intermediates in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: