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Structure of 642491-11-0
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This oxazole features a chiral, sterically hindered bis(oxazoline) architecture anchored by a phenylphosphinidene bridge, delivering high selectivity in asymmetric catalysis. The (4S,4′S)-configuration and tert-butyl substituents confer exceptional stability and solubility under standard reaction conditions.
This chiral bis(oxazole) ligand functions as a robust, bench-stable phosphine surrogate in transition metal catalysis, enabling efficient asymmetric transformations. Its sterically encumbered 4-tert-butyl substituents enhance selectivity and stability, while the rigid biphenyl backbone ensures defined spatial orientation. Designed for use in Pd-catalyzed cross-couplings and related processes, it facilitates high enantioselectivity with broad functional group tolerance and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: