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Structure of 64415-07-2
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7-(Trifluoromethyl)quinoline-4-thiol features a trifluoromethyl group at the 7-position and a thiol functionality at the 4-position of the quinoline scaffold. This electron-deficient heterocycle enables direct conjugation in bioorthogonal labeling, metal coordination, or polymer anchoring applications under standard conditions.
7-(Trifluoromethyl)quinoline-4-thiol serves as a versatile building block for heterocyclic synthesis, enabling efficient construction of quinoline-based scaffolds via C–S and C–C coupling reactions. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the thiol functionality offers reliable conjugation potential and orthogonal reactivity in multi-step sequences. Bench-stable and amenable to purification by chromatography or recrystallization, it functions effectively in both small-molecule drug discovery and materials chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: