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Structure of 64431-96-5
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2-Chloro-2,2-difluoroacetophenone is a difluorocarbene reagent, which is generally used in the synthesis of 2,2-difluoro enol silyl ethers, and gem-difluoromethene derived compounds.2-Chloro-2,2-difluoroacetophenone can be used:As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.As a precursor in the Baylis-Hillman reaction of fluoroalkyl ketones to obtain chlorodifluoromethyl containing products.As a substrate in the synthesis of propargyl alcohols using a novel ruthenium catalyst.
Bis-tris propane serves as a robust, bench-stable building block for the synthesis of functionalized heterocycles and peptide mimetics. Its triazine core enables efficient coupling reactions with diverse nucleophiles, offering high functional group tolerance and straightforward purification. This reagent facilitates rapid access to complex scaffolds in medicinal chemistry workflows, particularly in the development of kinase inhibitors and macrocyclic compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: