Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,7-Diazaspiro[4.4]nonane-7-carboxylic acid, 1,1-dimethylethyl ester

  • CAS No. 646055-63-2

  • Cat. No. CS-0000886
  • Purity≥97%
  • MDL No.MFCD09266216

*For research and further manufacturing use only, not for direct human use.

1,7-Diazaspiro[4.4]nonane-7-carboxylic acid, 1,1-dimethylethyl ester|CS-0000886

Structure of 646055-63-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 646055-63-2
  • Cat. No. CS-0000886
  • Purity ≥97%
  • MDL No. MFCD09266216
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂N₂O₂
  • Molecular Weight 226.32
  • Synonym(s) Tert-butyl 1,7-diazaspiro[4.4]nonane-7-carboxylate
  • SMILES O=C(OC(C)(C)C)N(CC1)CC21NCCC2

Description

This spirocyclic ester features a rigid 1,7-diazaspiro[4.4]nonane core with a tert-butyl ester group at the C7 position, offering enhanced stability and solubility in organic media. The structure integrates a protected carboxylic acid functionality ideal for modular synthesis in medicinal chemistry applications.

Application

1,7-Diazaspiro[4.4]nonane-7-carboxylic acid, 1,1-dimethylethyl ester serves as a versatile spirocyclic building block for medicinal chemistry and catalytic synthesis. The tert-butyl ester group provides excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. Its rigid, bicyclic scaffold enables precise spatial control in ligand design and target-oriented synthesis, while the pendant amine functionality supports diverse functionalization via standard coupling reactions.

Synthesis

  • Route1
    • 1,7-Diazaspiro[4.4]nonane-7-carboxylic acid, 1-(phenylmethyl)-, 1,1-dimethylethyl ester|CS-0000887
      646055-62-1
    • ~99%
    • In-stock
      1,7-Diazaspiro[4.4]nonane-7-carboxylic acid, 1,1-dimethylethyl ester|CS-0000886
      646055-63-2

    References

    • TARGACEPT, INC. Patent: WO2006/23630 A2, 2006 ; Location in patent: Page/Page column 58 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.7494
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 646055-63-2 sigma646055-63-2 manufacturer646055-63-2 price646055-63-2 structure646055-63-2 SDSbuy 646055-63-2646055-63-2 supplier646055-63-2 uses646055-63-2 molecular weightprice of 646055-63-2646055-63-2 chemical name formula of 646055-63-2
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label