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CS-W001157 4
Total: USD 88.00

(3AR,4S,5R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one

  • CAS No. 65025-95-8

  • Cat. No. CS-0542707
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3AR,4S,5R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one|CS-0542707

Structure of 65025-95-8

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General Information

  • CAS No. 65025-95-8
  • Cat. No. CS-0542707
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₃₄O₅Si
  • Molecular Weight 370.56
  • Synonym(s) 2H-Cyclopenta[b]furan-2-one, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]hexahydro-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)-
  • SMILES C(O[Si](C(C)(C)C)(C)C)[C@@H]1[C@@]2([C@](C[C@H]1OC3CCCCO3)(OC(=O)C2)[H])[H]

Synthesis

  • Route1
    • null|null
      110-87-2
    • null|null
      58707-50-9
    • ~95%
    • (3AR,4S,5R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one|CS-0542707
      65025-95-8

    References

    • Gonzalez-Gonzalez, Carlos A.; Fuentes-Benitez, Aydee; Cuevas-Yanez, Erick; Corona-Becerril, David; Gonzalez-Romero, Carlos; Gonzalez-Calderon, Davir Tetrahedron Letters, 2013 , vol. 54, # 21 p. 2726 - 2728
  • Route2
    • null|null
      69222-61-3
    • null|null
      18162-48-6
    • ~%
    • (3AR,4S,5R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one|CS-0542707
      65025-95-8

    References

    • Tetrahedron Letters, , vol. 32, # 35 p. 4557 - 4560
  • Route3
    • Imidazole Ondansetron Impurity|CS-0229601
      288-32-4
    • null|null
      69222-61-3
    • null|null
      18162-48-6
    • ~%
    • (3AR,4S,5R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one|CS-0542707
      65025-95-8

    References

    • ONO PHARMACEUTICAL CO., LTD.; Kambe, Tohru; Sugimoto, Isamu Patent: US2013/324577 A1, 2013 ; Location in patent: Paragraph 0286; 0287 ;

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   53.99
  • LogP   3.8716
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   5

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