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Structure of 653589-95-8
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Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a bench-stable boronate ester featuring a para-substituted aryl moiety. This compound integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering arylated products with high efficiency under standard conditions. The tetramethylcyclopentadienone core enhances stability and facilitates selective reaction at the boron center.
Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The pinacol borane moiety enables efficient C–C bond formation under mild conditions, with excellent functional group tolerance and straightforward purification. This reagent facilitates the construction of biaryl and heteroaryl scaffolds common in medicinal chemistry and materials science, offering high reproducibility in both academic and industrial synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: