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CS-W001157 4
Total: USD 88.00

N2,N6-Bis(tert-butoxycarbonyl)-D-lysine

  • CAS No. 65360-27-2

  • Cat. No. CS-W019314
  • Purity≥95%
  • MDL No.MFCD00076960
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N2,N6-Bis(tert-butoxycarbonyl)-D-lysine|CS-W019314

Structure of 65360-27-2

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Description

N2,N6-Bis(tert-butoxycarbonyl)-D-lysine is a protected D-amino acid derivative featuring two tert-butoxycarbonyl groups at the α-amino and ε-amino positions. This configuration enables stable incorporation into peptide chains during solid-phase synthesis, offering enhanced solubility and resistance to racemization under standard conditions. The bulky tert-butyl groups provide steric shielding, minimizing side reactions during coupling steps.

Application

N2,N6-Bis(tert-butoxycarbonyl)-D-lysine serves as a protected D-lysine building block for solid-phase peptide synthesis and the construction of bioactive heterocyclic scaffolds. The Boc groups provide excellent stability under basic conditions and facilitate selective deprotection, enabling orthogonal functionalization in complex peptide architectures. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for iterative synthesis workflows in medicinal chemistry and API development.

General Information

  • CAS No. 65360-27-2
  • Cat. No. CS-W019314
  • Purity ≥95%
  • MDL No. MFCD00076960
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₀N₂O₆
  • Molecular Weight 346.42
  • Synonym(s) None
  • SMILES O=C(O)[C@H](NC(OC(C)(C)C)=O)CCCCNC(OC(C)(C)C)=O

Computational Chemistry Data

  • TPSA   113.96
  • LogP   2.6593
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   7

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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