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Structure of 6542-47-8
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6-Formylnicotinic acid is a bench-stable, moisture-tolerant pyridine derivative bearing a formyl group at the 6-position and a carboxylic acid at the 3-position. This dual functionality enables direct coupling in peptide synthesis or conjugation strategies, where the aldehyde facilitates oxime ligation and the acid supports amide bond formation.
6-Formylnicotinic acid serves as a versatile building block for heterocyclic synthesis, enabling direct access to pyridine-based scaffolds via cyclization and functionalization reactions. Its ortho-formyl and carboxylic acid groups offer complementary reactivity for sequential transformations, facilitating the construction of medicinally relevant frameworks. The compound exhibits good bench stability and is readily purified by recrystallization, supporting reliable use in iterative synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: