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Structure of 655-14-1
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2,5-Difluoroterephthalic acid features a rigid aromatic core with two fluorine substituents positioned at the 2 and 5 ring positions, imparting enhanced electron-withdrawing character and improved solubility in polar solvents. This structural motif enables efficient integration into metal-organic frameworks and functional polymers, where its defined geometry supports precise network assembly under standard conditions.
2,5-Difluoroterephthalic acid serves as a valuable building block for the synthesis of fluorinated aromatic polymers and bioactive heterocycles. Its two carboxylic acid groups enable straightforward amide, ester, and imide formation, while the ortho-fluoro substituents offer enhanced electrophilicity for subsequent nucleophilic aromatic substitution. The compound exhibits good bench stability and facilitates purification via recrystallization, making it well-suited for scalable synthetic applications in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: