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Structure of 6554-61-6
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4,5-Dichloropyrimidine serves as a pivotal heterocyclic scaffold for constructing bioactive molecules. This electron-deficient pyrimidine core facilitates efficient nucleophilic substitution reactions, enabling rapid diversification at C4 and C5 positions. The molecule exhibits excellent stability under standard conditions and integrates readily into pharmaceutical intermediates, agrochemicals, and functional materials.
4,5-Dichloropyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient functionalization at C4 and C5 positions via palladium-catalyzed cross-coupling reactions. Its high reactivity and bench stability facilitate the construction of complex heterocyclic scaffolds, including substituted pyrimidines found in kinase inhibitors and antiviral agents. The dichloro substitution pattern provides orthogonal reactivity for sequential transformations, while the core structure exhibits excellent compatibility with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: