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Structure of 83942-10-3
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4,5-Dichloro-6-methylpyrimidine is a chlorinated pyrimidine derivative featuring two chlorine atoms at the 4 and 5 positions and a methyl group at the 6 position. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling direct coupling reactions via its reactive halogen sites. The molecule exhibits bench-stable handling characteristics and integrates efficiently into complex synthetic pathways for targeted compound libraries.
4,5-Dichloro-6-methylpyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds through nucleophilic substitution. The dichloro substituents provide orthogonal reactivity at C4 and C5 positions, facilitating sequential functionalization with diverse amines, thiols, or organometallic reagents. Its bench-stable nature and compatibility with standard coupling conditions make it well-suited for modular synthesis of bioactive molecules and heterocyclic intermediates.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: