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Structure of 65550-79-0
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2-Bromo-5-chloronicotinic acid is a halogenated pyridine carboxylic acid featuring bromo and chloro substituents at the 2- and 5-positions, respectively. This electron-deficient heterocycle integrates readily into cross-coupling reactions, serving as a key building block for pharmaceutical intermediates and agrochemicals. The molecule exhibits enhanced stability under standard bench conditions and demonstrates favorable solubility in polar organic solvents.
2-Bromo-5-chloronicotinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-bromine and meta-chlorine substituents enable selective metal-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates direct derivatization or salt formation. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for use in iterative synthetic sequences targeting complex nitrogen-containing scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: