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CS-W001157 4
Total: USD 88.00

Boc-Phe(4-NH2)-OMe

  • CAS No. 65615-90-9

  • Cat. No. CS-0154521
  • Purity≥98%
  • MDL No.MFCD11655908

*For research and further manufacturing use only, not for direct human use.

Boc-Phe(4-NH2)-OMe|CS-0154521

Structure of 65615-90-9

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General Information

  • CAS No. 65615-90-9
  • Cat. No. CS-0154521
  • Purity ≥98%
  • MDL No. MFCD11655908
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₂N₂O₄
  • Molecular Weight 294.35
  • Synonym(s) (S)-Methyl 3-(4-aminophenyl)-2-((tert-butoxycarbonyl)amino)propanoate
  • SMILES CC(C)(OC(N[C@H](C(OC)=O)CC1=CC=C(N)C=C1)=O)C

Description

Boc-Phe(4-NH2)-OMe features a para-aminomethylphenylalanine side chain with orthogonal protection: a Boc group on the amine and a methyl ester on the carboxylate. This dual protection enables selective deprotection during peptide synthesis, facilitating efficient incorporation of functionalized phenylalanine residues into complex sequences under standard conditions.

Application

Boc-Phe(4-NH₂)-OMe serves as a versatile building block for peptide synthesis, enabling the incorporation of para-aminophenylalanine motifs. The Boc group provides reliable protection of the α-amino function, while the methyl ester facilitates efficient coupling and subsequent hydrolysis. The pendant 4-amino group offers a handle for further derivatization via amide bond formation or conjugation, making this intermediate valuable in constructing bioactive peptides and functionalized scaffolds with enhanced solubility and synthetic flexibility.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330

Quality Control

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   1.8776
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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