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Structure of 65632-62-4
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This chiral building block features a protected hexahydropyridazine core with a benzyloxycarbonyl group and carboxylic acid functionality. It integrates readily into peptide-like architectures, offering a rigid, electron-deficient scaffold for medicinal chemistry applications. The benzyl protecting group enables orthogonal deprotection under standard hydrogenolysis conditions.
(S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid serves as a stereochemically defined building block for the synthesis of pyridazinone-based scaffolds. Its benzyloxycarbonyl (Cbz) group provides robust protection of the amine, enabling selective deprotection and orthogonal functionalization. The carboxylic acid functionality facilitates coupling reactions with amines or alcohols under standard conditions. This compound exhibits good bench stability and simplifies purification in multi-step syntheses, making it valuable for medicinal chemistry campaigns targeting heterocyclic compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: