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Structure of 6575-13-9
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2,6-Dimethylbenzonitrile features a nitrile group flanked by two methyl substituents at the 2 and 6 positions of the benzene ring, creating a sterically hindered, electron-deficient aromatic system. This configuration enhances stability and directs electrophilic substitution selectively. The compound serves as a valuable building block in synthetic organic chemistry, particularly for constructing functionalized arenes under mild conditions. Its bench-stable nature facilitates handling in routine laboratory workflows.
2,6-Dimethylbenzonitrile serves as a robust building block in medicinal chemistry and materials science, offering enhanced steric shielding around the nitrile group due to ortho-methyl substitution. Its bench-stable nature, combined with high functional group tolerance, enables reliable use in nucleophilic transformations, transition-metal-catalyzed couplings, and heterocycle synthesis. The aromatic core facilitates efficient purification and crystallization, making it well-suited for scale-up and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: