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CS-W001157 4
Total: USD 88.00

5-Amino-4-fluoro-2-methylbenzoic acid

  • CAS No. 658085-42-8

  • Cat. No. CS-0179650
  • Purity≥98%
  • MDL No.MFCD20658858
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Amino-4-fluoro-2-methylbenzoic acid|CS-0179650

Structure of 658085-42-8

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Description

5-Amino-4-fluoro-2-methylbenzoic acid features a trifunctional aromatic core with electron-donating amino and methyl groups, paired with a fluorine atom that enhances metabolic stability. This configuration enables direct integration into bioactive scaffolds for pharmaceutical development.

Application

5-Amino-4-fluoro-2-methylbenzoic acid serves as a versatile building block for pharmaceutical intermediates and bioactive heterocycles. Its ortho-substituted scaffold enables selective functionalization in late-stage diversification, while the carboxylic acid group facilitates amide coupling and salt formation. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step synthesis workflows requiring precise regiocontrol and functional group tolerance.

General Information

  • CAS No. 658085-42-8
  • Cat. No. CS-0179650
  • Purity ≥98%
  • MDL No. MFCD20658858
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈FNO₂
  • Molecular Weight None
  • Synonym(s) 5-Amino-4-fluoro-2-methyl-benzoic acid
  • SMILES O=C(O)C1=CC(N)=C(F)C=C1C

Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.41452
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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