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Structure of 6602-54-6
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2-Chloro-3-cyanopyridine features a strategically positioned cyano group flanked by a chlorine atom on the pyridine ring, enabling selective functionalization in heterocyclic synthesis. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and agrochemical building blocks under mild conditions.
2-Chloro-3-cyanopyridine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based heterocycles via palladium-catalyzed cross-coupling reactions. Its ortho-chloro and cyano groups offer complementary reactivity for sequential functionalization, with the cyano group amenable to hydrolysis or nucleophilic addition. Bench-stable and readily purified by flash chromatography, it functions reliably in multi-step syntheses of API scaffolds and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312+H332-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: