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Structure of 66107-32-2
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4-Cyanophenyl trifluoromethanesulfonate serves as a highly reactive arylating agent, featuring a triflate leaving group that enables efficient coupling under mild conditions. The para-cyano substituent enhances electrophilicity and stabilizes reaction intermediates. This bench-stable reagent integrates seamlessly into cross-coupling protocols for constructing functionalized biaryls in synthetic organic chemistry.
4-Cyanophenyl trifluoromethanesulfonate serves as a robust arylating agent in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its triflate leaving group ensures high reactivity under standard conditions, while the electron-withdrawing cyano group enhances stability and facilitates purification. This compound functions reliably in Suzuki-Miyaura and Stille couplings, offering excellent functional group tolerance and bench stability for routine synthetic workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H290-H314
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Precautionary Statements : P234-P264-P280-P301+P330+P331-P304+P340-P363-P405-P406-P501
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Lot numbers can be found on the outside label of a product: