1-Bromo-5-fluoro-4-methoxy-2-nitrobenzene

Name: 1-Bromo-5-fluoro-4-methoxy-2-nitrobenzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 661463-13-4
Cat. No. CS-0041446
Purity≥98%
MDL No.MFCD11100974

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Bromo-5-fluoro-4-methoxy-2-nitrobenzene|CS-0041446

Structure of 661463-13-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

1-Bromo-5-fluoro-4-methoxy-2-nitrobenzene features a strategically positioned bromine atom flanked by electron-withdrawing nitro and fluoro groups, enabling efficient palladium-catalyzed cross-coupling. The methoxy substituent enhances solubility and modulates reactivity, while the overall electronic profile supports selective functionalization in complex synthesis.

Application

1-Bromo-5-fluoro-4-methoxy-2-nitrobenzene serves as a versatile building block in medicinal chemistry and materials synthesis, enabling palladium-catalyzed cross-coupling reactions due to its ortho-halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluoro and nitro substituents offer orthogonal functionalization potential. Its bench-stable nature and compatibility with standard purification protocols make it ideal for multi-step syntheses of complex heterocyclic scaffolds and API intermediates.

General Information

CAS No. 661463-13-4
Cat. No. CS-0041446
Purity ≥98%
MDL No. MFCD11100974
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrFNO₃
Molecular Weight 250.02
Synonym(s) 4-broMo-2-fluoro-5-nitrophenyl Methyl ether
SMILES O=[N+](C1=CC(OC)=C(F)C=C1Br)[O-]

Computational Chemistry Data

TPSA 52.37
LogP 2.505
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Nitro compounds

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

661463-13-4 sigma661463-13-4 manufacturer661463-13-4 price661463-13-4 structure661463-13-4 SDSbuy 661463-13-4661463-13-4 supplier661463-13-4 uses661463-13-4 molecular weightprice of 661463-13-4661463-13-4 chemical name formula of 661463-13-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-Bromo-5-fluoro-4-methoxy-2-nitrobenzene

CAS No. 661463-13-4

Recommended Products