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Structure of 6622-92-0
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2,6-Dimethylpyrimidin-4-ol features a sterically hindered pyrimidine core with a phenolic hydroxyl group, enabling robust hydrogen bonding and enhanced solubility in polar solvents. This bench-stable compound integrates readily into heterocyclic synthesis, serving as a key scaffold for medicinal chemistry and catalyst design.
2,6-Dimethylpyrimidin-4-ol serves as a versatile building block in medicinal chemistry, enabling the construction of pyrimidine-based scaffolds prevalent in kinase inhibitors and antiviral agents. Its stability under standard reaction conditions, combined with predictable reactivity at the C4 hydroxyl group, facilitates straightforward derivatization via etherification, esterification, or metal-catalyzed coupling. The methyl groups at C2 and C6 enhance solubility and modulate electronic properties, offering favorable handling characteristics for high-throughput synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: