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CS-W001157 4
Total: USD 88.00

NH2-PEG4-CH2CH2COOH

  • CAS No. 663921-15-1

  • Cat. No. CS-0041310
  • Purity≥95%
  • MDL No.MFCD11041129

*For research and further manufacturing use only, not for direct human use.

NH2-PEG4-CH2CH2COOH|CS-0041310

Structure of 663921-15-1

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General Information

  • CAS No. 663921-15-1
  • Cat. No. CS-0041310
  • Purity ≥95%
  • MDL No. MFCD11041129
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₃NO₆
  • Molecular Weight 265.30
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOCCOCCN

Description

NH2-PEG4-CH2CH2COOH features a linear PEG4 spacer flanked by an amine handle and a terminal carboxylic acid, enabling dual conjugation versatility. This bifunctional linker facilitates site-specific coupling in bioconjugation workflows, offering enhanced solubility and stability under physiological conditions.

Application

NH₂-PEG₄-CH₂CH₂COOH serves as a versatile bifunctional linker for conjugation workflows, combining the solubility and stability of a tetra(ethylene glycol) chain with orthogonal reactive handles. The terminal amine enables efficient coupling to carboxylated surfaces or biomolecules, while the β-carboxylic acid facilitates further derivatization via amide or ester formation. Its well-defined structure supports reliable purification and consistent performance in peptide, antibody-drug conjugate, and nanoparticle functionalization applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.24
  • LogP   -0.5138
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   14

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