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Structure of 66490-31-1
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4-Chloro-3-methylbenzo[b]thiophene-2-carboxylic acid features a rigid heteroaromatic core with orthogonal electron-withdrawing chlorine and carboxylic acid groups, enabling direct integration into pharmaceutical scaffolds. The methyl substituent enhances lipophilicity and metabolic stability, while the carboxylic acid facilitates conjugation or salt formation for improved solubility in formulation workflows.
4-Chloro-3-methylbenzo[b]thiophene-2-carboxylic acid serves as a versatile building block for the synthesis of biologically active heterocycles, particularly in medicinal chemistry and agrochemical development. The carboxylic acid functionality enables direct coupling reactions, while the chloro and methyl groups provide sites for further functionalization via palladium-catalyzed cross-coupling or electrophilic substitution. Its stability under standard reaction conditions and compatibility with diverse transformations make it well-suited for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: