Boc-4-Abz-OH

Name: Boc-4-Abz-OH
Brand: ChemScene
Availability: InStock
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CAS No. 66493-39-8
Cat. No. CS-W007493
Purity≥98%
MDL No.MFCD00037428

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 66493-39-8

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Description

Boc-4-Abz-OH is a bench-stable, moisture-tolerant building block featuring a protected amine and a para-aminobenzoic acid (Abz) chromophore. This derivative integrates seamlessly into peptide synthesis workflows, enabling site-specific labeling or fluorescent tagging in bioconjugation applications.

Application

Boc-4-Abz-OH serves as a versatile building block for peptide synthesis and peptidomimetic design, enabling efficient incorporation of the 4-aminobenzoic acid (4-Abz) moiety. The Boc group provides orthogonal protection for the amine, allowing selective deprotection under mild acidic conditions. This derivative exhibits excellent bench stability, facilitates straightforward purification, and participates reliably in standard coupling reactions, making it ideal for constructing bioactive peptides and heterocyclic scaffolds in medicinal chemistry workflows.

General Information

CAS No. 66493-39-8
Cat. No. CS-W007493
Purity ≥98%
MDL No. MFCD00037428
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₅NO₄
Molecular Weight 237.25
Synonym(s) 4-[(tert-butoxycarbonyl)amino]benzoic acid
SMILES O=C(O)C1=CC=C(NC(OC(C)(C)C)=O)C=C1

Computational Chemistry Data

TPSA 75.63
LogP 2.7318
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

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Boc-4-Abz-OH

CAS No. 66493-39-8

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