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Structure of 666735-07-5
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7-Bromo-6-methoxyisoquinoline is a halogenated isoquinoline derivative featuring a bromine atom at the 7-position and a methoxy group at the 6-position. This electron-deficient scaffold integrates readily into transition metal-catalyzed coupling reactions, offering enhanced reactivity in C–H functionalization and cross-coupling processes. The para-substituted aryl system provides favorable steric and electronic profiles for modular synthesis in medicinal chemistry and materials science applications.
7-Bromo-6-methoxyisoquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen reactivity. The methoxy group enhances electron density at the isoquinoline core, improving stability and facilitating selective functionalization. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: