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Structure of 66787-75-5
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1-Methyl-1H-imidazol-5-amine features a methylated imidazole core with a primary amine at the 5-position, delivering enhanced solubility and nucleophilicity. This configuration enables direct incorporation into heterocyclic scaffolds and facilitates efficient coupling reactions under mild conditions. The compound serves as a key building block in medicinal chemistry and catalyst design.
1-Methyl-1H-imidazol-5-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its well-defined nucleophilicity at the 5-position facilitates direct functionalization and transition-metal-catalyzed coupling reactions. The molecule exhibits excellent bench stability, ease of purification, and compatibility with common protecting group strategies, making it ideal for modular synthesis of imidazole-based scaffolds in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: