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Structure of 668-45-1
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2-Chloro-6-fluorobenzonitrile features a dual halogen substitution pattern that enhances reactivity in cross-coupling processes. The electron-deficient aromatic ring pairs effectively with nucleophilic partners, while the nitrile group provides a versatile handle for downstream functionalization. This compound serves as a key intermediate in pharmaceutical and agrochemical synthesis.
2-Chloro-6-fluorobenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the ortho position relative to the nitrile group. Its dual halogen substituents facilitate palladium-catalyzed cross-coupling reactions, while the nitrile moiety offers compatibility with nucleophilic additions and cyclizations. The compound exhibits good bench stability and is readily purified by distillation or recrystallization, supporting scalable applications in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: