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CS-W001157 4
Total: USD 88.00

1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid

  • CAS No. 67058-74-6

  • Cat. No. CS-0044734
  • Purity≥95%
  • MDL No.MFCD11845479
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid|CS-0044734

Structure of 67058-74-6

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Description

1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid features a fused heterocyclic core with a carboxylic acid at the 3-position, enabling direct conjugation in medicinal chemistry scaffolds. The electron-deficient pyrrolopyridine framework supports robust coupling reactions and enhances metabolic stability in bioactive molecules. This bench-stable reagent integrates efficiently into diverse synthetic pathways requiring rigid, planar aromatic systems.

Application

1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling and functionalization reactions. Its carboxylic acid functionality facilitates direct amide formation, esterification, and metal-mediated transformations, while the fused polycyclic core exhibits favorable bench stability and compatibility with diverse reaction conditions. This compound functions as a key structural motif in the synthesis of kinase inhibitors and other targeted therapeutics.

General Information

  • CAS No. 67058-74-6
  • Cat. No. CS-0044734
  • Purity ≥95%
  • MDL No. MFCD11845479
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₂
  • Molecular Weight 162.15
  • Synonym(s) None
  • SMILES O=C(C1=CNC2=C1C=CN=C2)O

Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.2611
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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