2,4-Difluoro-5-nitrobenzonitrile

Name: 2,4-Difluoro-5-nitrobenzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 67152-20-9
Cat. No. CS-W003416
Purity≥98%
MDL No.MFCD07772030

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,4-Difluoro-5-nitrobenzonitrile|CS-W003416

Structure of 67152-20-9

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2,4-Difluoro-5-nitrobenzonitrile features a trifunctional aromatic core with electron-withdrawing fluorine, nitro, and nitrile groups positioned for orthogonal reactivity. This bench-stable scaffold enables direct incorporation into diverse synthetic sequences, including nucleophilic substitutions and transition-metal-catalyzed couplings. The strategic placement of substituents enhances regioselective functionalization in pharmaceutical and agrochemical development.

Application

2,4-Difluoro-5-nitrobenzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of functionalized heterocycles via nucleophilic aromatic substitution. Its trifunctional profile—comprising two fluorine leaving groups, a nitro group for reduction or displacement, and a nitrile for hydrolysis or coupling—facilitates modular synthesis. Bench-stable and compatible with standard reaction conditions, it supports scalable derivatization in API development workflows.

General Information

CAS No. 67152-20-9
Cat. No. CS-W003416
Purity ≥98%
MDL No. MFCD07772030
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₂F₂N₂O₂
Molecular Weight 184.10
Synonym(s) 5-Cyano-2,4-difluoronitrobenzene
SMILES N#Cc1cc([N+](=O)[O-])c(cc1F)F

Computational Chemistry Data

TPSA 66.93
LogP 1.74468
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2,4-Difluoro-5-nitrobenzonitrile sigma2,4-Difluoro-5-nitrobenzonitrile manufacturer2,4-Difluoro-5-nitrobenzonitrile price2,4-Difluoro-5-nitrobenzonitrile structure2,4-Difluoro-5-nitrobenzonitrile SDSbuy 2,4-Difluoro-5-nitrobenzonitrile2,4-Difluoro-5-nitrobenzonitrile supplier2,4-Difluoro-5-nitrobenzonitrile uses2,4-Difluoro-5-nitrobenzonitrile molecular weightprice of 2,4-Difluoro-5-nitrobenzonitrile2,4-Difluoro-5-nitrobenzonitrile chemical name formula of 2,4-Difluoro-5-nitrobenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,4-Difluoro-5-nitrobenzonitrile

CAS No. 67152-20-9

Recommended Products