Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 672-58-2
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
3-(Trifluoromethyl)benzenesulfonamide features a strongly electron-withdrawing trifluoromethyl group positioned ortho to the sulfonamide, enhancing its acidity and metabolic stability. This combination imparts robust solubility in polar organic solvents and resistance to hydrolytic degradation. The molecule serves as a key scaffold in medicinal chemistry for kinase inhibitors and enzyme modulators due to its ability to form strong hydrogen bonds and occupy hydrophobic pockets.
3-(Trifluoromethyl)benzenesulfonamide serves as a robust sulfonamide building block in medicinal chemistry, offering enhanced metabolic stability and lipophilicity due to the electron-withdrawing trifluoromethyl group. It functions effectively in amide coupling, nucleophilic substitution, and transition-metal-catalyzed cross-coupling reactions, with good bench stability and ease of purification. Widely employed in the synthesis of kinase inhibitors and other bioactive heterocycles, it enables efficient access to complex scaffolds under standard reaction conditions.
|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P302+P352-P304+P340
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: