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Structure of 67472-44-0
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4-(Hydroxymethyl)benzene-1-sulfonamide features a sulfonamide group attached to a para-hydroxymethyl-substituted benzene ring, combining strong hydrogen-bonding capacity with enhanced solubility. This scaffold integrates well into bioactive molecules requiring polar functionality and metabolic stability, particularly in kinase inhibitor design and medicinal chemistry lead optimization.
4-(Hydroxymethyl)benzene-1-sulfonamide serves as a versatile building block in medicinal chemistry, enabling the introduction of both sulfonamide and primary alcohol functionalities. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient derivatization for targeted compound libraries. The molecule functions as a key intermediate in the synthesis of bioactive heterocycles and sulfonamide-containing pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: