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CS-W001157 4
Total: USD 88.00

(S)-1-Boc-2-isobutyl-piperazine

  • CAS No. 674792-06-4

  • Cat. No. CS-W020512
  • Molecule weight242.36
  • Purity≥95%
  • MDL No.MFCD03787916

*For research and further manufacturing use only, not for direct human use.

(S)-1-Boc-2-isobutyl-piperazine|CS-W020512

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General Information

  • CAS No. 674792-06-4
  • Cat. No. CS-W020512
  • Purity ≥95%
  • MDL No. MFCD03787916
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₆N₂O₂
  • Molecular Weight 242.36
  • Synonym(s) (S)-tert-butyl 2-isobutylpiperazine-1-carboxylate
  • SMILES O=C(OC(C)(C)C)N1[C@H](CNCC1)CC(C)C

Description

(S)-1-Boc-2-isobutyl-piperazine is a chiral piperazine derivative featuring a Boc-protected nitrogen and a sterically hindered isobutyl substituent. This configuration enables selective incorporation into complex molecular architectures, particularly in medicinal chemistry scaffolds requiring defined stereochemistry. The Boc group offers reliable protection under standard conditions, facilitating subsequent deprotection and functionalization.

Application

(S)-1-Boc-2-isobutyl-piperazine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive amines through selective deprotection and functionalization. Its Boc group ensures bench stability and ease of purification, while the isobutyl substituent provides steric differentiation and enhanced solubility. The piperazine core facilitates hydrogen bonding and improves pharmacokinetic properties in drug candidates, making it a reliable scaffold for constructing diverse heterocyclic systems via standard coupling and cyclization protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.2414
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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