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Structure of 67496-29-1
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This brominated benzodioxole methanamine integrates a reactive amine handle and electron-deficient aromatic core, enabling direct coupling in cross-coupling and bioconjugation workflows. The pendant amine facilitates derivatization under mild conditions, while the 6-bromo substituent supports palladium-catalyzed functionalization.
(6-Bromobenzo[d][1,3]dioxol-5-yl)methanamine serves as a versatile building block for medicinal chemistry and materials synthesis, enabling efficient incorporation of brominated catechol motifs into target molecules. The primary amine functions as a handle for Suzuki-Miyaura coupling, reductive amination, or amide formation, while the 1,3-benzodioxole ring provides metabolic stability and favorable pharmacokinetic properties. Bench-stable and readily purified by standard chromatography, it facilitates scalable synthesis of bioactive heterocycles and functionalized aryl scaffolds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: