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CS-W001157 4
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1-Methyl-1H-1,2,3-triazol-4-amine

  • CAS No. 67545-00-0

  • Cat. No. CS-0099489
  • Molecule weight98.11
  • Purity≥98%
  • MDL No.MFCD09055315

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-1,2,3-triazol-4-amine|CS-0099489

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General Information

  • CAS No. 67545-00-0
  • Cat. No. CS-0099489
  • Purity ≥98%
  • MDL No. MFCD09055315
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆N₄
  • Molecular Weight 98.11
  • Synonym(s) 4-Amino-1-methyl-1,2,3-triazol
  • SMILES NC1=CN(N=N1)C

Description

1-Methyl-1H-1,2,3-triazol-4-amine features a reactive triazole nitrogen that integrates readily into click chemistry workflows. This bench-stable, moisture-tolerant amine serves as a key building block for bioconjugation and drug discovery applications.

Application

1-Methyl-1H-1,2,3-triazol-4-amine serves as a versatile building block in medicinal chemistry and synthetic organic chemistry. Its primary amine functionality enables straightforward derivatization via amidation, alkylation, and coupling reactions. The molecule exhibits excellent bench stability, facilitates purification by standard chromatographic methods, and functions effectively in click chemistry applications due to its compatibility with copper-catalyzed azide-alkyne cycloadditions.

Synthesis

  • Route1
    • Ethyl (1-methyl-1H-1,2,3-triazol-4-yl)carbamate|CS-0562404
      99848-29-0
    • ~%
    • In-stock
      1-Methyl-1H-1,2,3-triazol-4-amine|CS-0099489
      67545-00-0

    References

    • Pedersen Acta Chemica Scandinavica (1947-1973), 1959 , vol. 13, p. 888,890

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   56.73
  • LogP   -0.6027
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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