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Structure of 67608-58-6
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4-Amino-2-hydroxybenzonitrile features a strategically positioned amino group and hydroxyl moiety flanking a nitrile functionality, enabling dual-directional conjugation in synthetic sequences. This ortho-substituted scaffold delivers enhanced solubility and reactivity under standard conditions, facilitating efficient incorporation into bioactive heterocycles and functional polymers.
4-Amino-2-hydroxybenzonitrile serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via cyclization or coupling reactions. Its ortho-hydroxyl and amino groups provide strong coordination for metal catalysis and facilitate downstream derivatization. The nitrile group offers high functional group tolerance and compatibility with standard transformations such as hydrolysis or nucleophilic addition. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses requiring regioselective reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: