6-Chloroimidazo[1,2-b]pyridazine

Name: 6-Chloroimidazo[1,2-b]pyridazine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 6775-78-6
Cat. No. CS-D1118
Purity≥95%
MDL No.MFCD07778345

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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6-Chloroimidazo[1,2-b]pyridazine|CS-D1118

Structure of 6775-78-6

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Description

6-Chloroimidazo[1,2-b]pyridazine is a heterocyclic compound featuring a chlorinated imidazopyridazine core. This electron-deficient scaffold serves as a key structural motif in medicinal chemistry, enabling direct incorporation into bioactive molecules. The chlorine substituent enhances electrophilicity at the adjacent ring position, facilitating downstream functionalization via nucleophilic substitution or transition-metal-catalyzed coupling. Its bench-stable nature supports straightforward handling and integration into synthetic sequences under standard conditions.

Application

6-Chloroimidazo[1,2-b]pyridazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to imidazopyridazine scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. The chlorine atom facilitates nucleophilic substitution reactions under mild conditions, allowing for rapid diversification at the C6 position. Its stability under standard reaction conditions and compatibility with common coupling protocols make it ideal for modular synthesis workflows.

General Information

CAS No. 6775-78-6
Cat. No. CS-D1118
Purity ≥95%
MDL No. MFCD07778345
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄ClN₃
Molecular Weight None
Synonym(s) 6-chloroimidazo(2,1-f)pyridazine
SMILES ClC1=NN2C(C=C1)=NC=C2

Computational Chemistry Data

TPSA 30.19
LogP 1.3827
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridazine compounds

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6-Chloroimidazo[1,2-b]pyridazine

CAS No. 6775-78-6

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