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Structure of 67914-60-7
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1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone features a hydroxylated phenyl group linked via piperazine to a ketone moiety, offering enhanced solubility and hydrogen-bonding capacity. This scaffold integrates readily into bioactive molecule design, particularly in CNS-targeted compounds and kinase inhibitors.
1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its piperazine core provides favorable solubility and metabolic stability, while the phenolic hydroxyl group offers a handle for derivatization via etherification or conjugation. The acetyl moiety enhances lipophilicity and supports further functionalization. This compound exhibits bench stability and facilitates purification through standard chromatographic methods, making it well-suited for iterative synthesis campaigns in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352
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Lot numbers can be found on the outside label of a product: