(S)-1-(2-Fluorophenyl)ethanamine

Name: (S)-1-(2-Fluorophenyl)ethanamine
Brand: ChemScene
Availability: InStock
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CAS No. 68285-25-6
Cat. No. CS-D0618
Purity≥96%
MDL No.MFCD03092994

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(S)-1-(2-Fluorophenyl)ethanamine|CS-D0618

Structure of 68285-25-6

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Description

(S)-1-(2-Fluorophenyl)ethanamine is a chiral building block featuring a fluorinated aromatic ring and a stereodefined amine center. This configuration enables selective incorporation into bioactive molecules, particularly in medicinal chemistry scaffolds requiring precise spatial orientation. The compound exhibits enhanced metabolic stability compared to non-fluorinated analogs and is compatible with standard coupling protocols under ambient conditions.

Application

(S)-1-(2-Fluorophenyl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of enantioselective pharmaceuticals. Its fluorinated aryl group enhances metabolic stability and modulates bioavailability. The molecule exhibits robust bench stability, facilitates straightforward purification via distillation or chromatography, and participates reliably in standard amine transformations—such as alkylation, acylation, and coupling reactions—without significant side reactivity.

General Information

CAS No. 68285-25-6
Cat. No. CS-D0618
Purity ≥96%
MDL No. MFCD03092994
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀FN
Molecular Weight 139.17
Synonym(s) (S)-1-(2-Fluorophenyl)ethylamine
SMILES FC1=CC=CC=C1[C@H](C)N

Computational Chemistry Data

TPSA 26.02
LogP 1.8454
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-1-(2-Fluorophenyl)ethanamine

CAS No. 68285-25-6

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