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Structure of 68703-67-3
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4-Amino-1H-pyrazole-3-carbonitrile features a conjugated pyrazole core bearing both amino and nitrile functionalities, enabling versatile participation in transition-metal-catalyzed couplings and heterocyclic elaboration. The electron-rich amine group facilitates nucleophilic addition, while the carbonitrile acts as an electrophilic anchor for derivatization under mild conditions. This bifunctional scaffold supports efficient access to bioactive nitrogen-containing architectures.
4-Amino-1H-pyrazole-3-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazole-based heterocycles. Its dual functional groups—primary amine and nitrile—facilitate diverse downstream transformations, including amidation, cyclization, and metal-catalyzed coupling reactions. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for scale-up and routine synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: