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Structure of 68755-42-0
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4-(Trifluoromethyl)-1-indanone features a trifluoromethyl group at the 4-position of an indanone scaffold, imparting strong electron-withdrawing character and enhanced metabolic stability. This configuration supports its utility in medicinal chemistry for modulating pharmacokinetic properties. The compound serves as a key intermediate in synthesizing bioactive molecules and functional materials.
4-(Trifluoromethyl)-1-indanone serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive indanone derivatives through standard functional group transformations. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the ketone functionality supports nucleophilic additions, reductive amination, and transition-metal-catalyzed couplings. Bench-stable and amenable to purification via recrystallization, it functions reliably in multi-step syntheses of pharmaceutical intermediates and heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: