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Structure of 69034-12-4
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2-Chloro-5-(trifluoromethyl)pyrimidine serves as a key heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its electron-deficient pyrimidine core, combined with the strong inductive effect of the trifluoromethyl group, enables efficient coupling reactions. This compound exhibits excellent stability under standard conditions and facilitates the construction of complex nitrogen-containing architectures.
2-Chloro-5-(trifluoromethyl)pyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient C–N and C–C coupling reactions. Its electron-deficient pyrimidine core exhibits excellent stability and compatibility with palladium-catalyzed cross-coupling protocols. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the chloro substituent provides a reliable handle for nucleophilic substitution under mild conditions. This compound functions effectively in the construction of heterocyclic scaffolds relevant to drug discovery programs.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: