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CS-W001157 4
Total: USD 88.00

Tripropargylamine

  • CAS No. 6921-29-5

  • Cat. No. CS-0197371
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tripropargylamine|CS-0197371

Structure of 6921-29-5

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General Information

  • CAS No. 6921-29-5
  • Cat. No. CS-0197371
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉N
  • Molecular Weight 131.17
  • Synonym(s) Trispropargylamine
  • SMILES C#CCN(CC#C)CC#C

Description

Bromo-PEG1-CH2CO2H is a PEG linker containing a bromide group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.

Application

Tripropargylamine serves as a versatile trifunctional building block for click chemistry and heterocyclic synthesis. Its three terminal alkyne groups enable efficient CuAAC and strain-promoted cycloadditions, facilitating the construction of triazolyl-linked scaffolds. The molecule exhibits excellent bench stability, facilitates straightforward purification via chromatography, and demonstrates broad functional group tolerance in multicomponent coupling reactions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   3.24
  • LogP   0.188
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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