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CS-W001157 4
Total: USD 88.00

Propane, 1-chloro-3-iodo-

  • CAS No. 6940-76-7

  • Cat. No. CS-W018493
  • Molecule weight204.44
  • Purity≥97%
  • MDL No.MFCD00001096

*For research and further manufacturing use only, not for direct human use.

Propane, 1-chloro-3-iodo-|CS-W018493

Structure of 6940-76-7

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General Information

  • CAS No. 6940-76-7
  • Cat. No. CS-W018493
  • Purity ≥97%
  • MDL No. MFCD00001096
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆ClI
  • Molecular Weight 204.44
  • Synonym(s) Propane, 1-chloro-3-iodo-
  • SMILES ICCCCl

Description

1-Chloro-3-iodopropane undergoes asymmetric -alkylation with N-sulfinyl imidates to yield 2-substituted N-tert-butanesulfinyl-5-chloropentanimidates. Electroreduction of 1-chloro-3-iodopropane at glassy carbon electrode in dimethylformamide containing tetra-n-butylammonium perchlorate has been investigated by cyclic voltammetry. It also participates in conjugate addition of alkyl iodides to ,-unsaturated nitriles in water.1-Chloro-3-iodopropane has been used in the synthesis of:N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid, an inhibitor of glycinamide ribonucleotide transformylase (GAR Tfase) and aminoimidazole carboxamide ribonucleotide transformylase (AICAR Tfase)interesting proton sponge type molecule quino[7,8-h]quinoline

Synthesis

  • Route1
    • null|null
      109-70-6
    • ~94%
    • In-stock
      Propane, 1-chloro-3-iodo-|CS-W018493
      6940-76-7

    References

    • Militzer; Schomenauer; Otte; Puls; Hain; Brase; De Meijere Synthesis, 1993 , # 10 p. 998 - 1012
  • Route2
    • null|null
      54509-73-8
    • In-stock
      Iodochloromethane|CS-0015110
      593-71-5
    • ~%
    • In-stock
      Propane, 1-chloro-3-iodo-|CS-W018493
      6940-76-7

    References

    • Journal of the American Chemical Society, , vol. 72, p. 2213
  • Route3
    • null|null
      627-30-5
    • ~%
    • In-stock
      Propane, 1-chloro-3-iodo-|CS-W018493
      6940-76-7

    References

    • Journal of the American Chemical Society, , vol. 55, p. 2927,2930

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.0503
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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