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Structure of 69816-35-9
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6-(Trifluoromethyl)pyrazin-2-amine features a trifluoromethyl group at the 6-position of the pyrazine ring, imparting enhanced electron-withdrawing character and metabolic stability. This nitrogen-rich heterocycle integrates readily into pharmaceutical scaffolds, offering improved solubility and binding affinity in targeted kinase inhibitors and bioactive molecule design.
6-(Trifluoromethyl)pyrazin-2-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation of the electron-withdrawing trifluoromethyl group into pyrazine-based scaffolds. Its stability under standard synthetic conditions and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient diversification. Functions as a key intermediate for targeted heterocyclic compound synthesis, particularly in kinase inhibitor and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: