Boc-D-Chg-OH

Name: Boc-D-Chg-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 70491-05-3
Cat. No. CS-W012548
Purity≥97%
MDL No.MFCD00133629

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 70491-05-3

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Description

Boc-D-Chg-OH is a protected D-2,3-diaminopropionic acid derivative featuring a tert-butoxycarbonyl group at the α-amino position. This bench-stable reagent facilitates efficient incorporation of D-Chg residues into peptide sequences under standard coupling conditions. The Boc protection enables selective deprotection during synthesis workflows.

Application

Boc-D-Chg-OH serves as a stable, bench-ready building block for the synthesis of D-chloroglycine-containing peptides and heterocyclic scaffolds. Its N-Boc protection ensures compatibility with standard coupling protocols, while the hydroxyl group provides a handle for selective derivatization. The compound exhibits excellent functional group tolerance and facilitates efficient incorporation into complex molecular architectures.

General Information

CAS No. 70491-05-3
Cat. No. CS-W012548
Purity ≥97%
MDL No. MFCD00133629
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₂₃NO₄
Molecular Weight 257.33
Synonym(s) None
SMILES O=C([C@@H](C1CCCCC1)NC(OC(C)(C)C)=O)O

Computational Chemistry Data

TPSA 75.63
LogP 2.5446
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Glycine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Boc-D-Chg-OH

CAS No. 70491-05-3

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