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CS-W001157 4
Total: USD 88.00

EGNHS

  • CAS No. 70539-42-3

  • Cat. No. CS-0108027
  • Purity≥97%
  • MDL No.MFCD00049057

*For research and further manufacturing use only, not for direct human use.

EGNHS|CS-0108027

Structure of 70539-42-3

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General Information

  • CAS No. 70539-42-3
  • Cat. No. CS-0108027
  • Purity ≥97%
  • MDL No. MFCD00049057
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₀N₂O₁₂
  • Molecular Weight 456.36
  • Synonym(s) EGS crosslinker
  • SMILES O=C(OCCOC(CCC(ON1C(CCC1=O)=O)=O)=O)CCC(ON2C(CCC2=O)=O)=O

Description

Crosslinking via amine-specific N-hydroxysuccinimide ester moieties, Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) (CAS 70539-42-3) enables site-selective conjugation in PROTAC assembly through stable amide bond formation.

Application

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) (CAS 70539-42-3) cross-links primary amines in biomolecules via stable amide bonds, enabling precise conjugation in protein and peptide engineering. It drives efficient bioconjugation. This setup streamlines the creation of immunoassays, targeted drug delivery systems, and functionalized surfaces with minimal side reactions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   179.96
  • LogP   -1.1524
  • H_Acceptors   12
  • H_Donors   0
  • Rotatable_Bonds   11

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